The Vederas Group
Department of Chemistry
The University of Alberta

Selected Publications

Selected Recent Publications (from over 340 total):

(click here for full list of publications)

Acedo J.Z.; Chiorean, S.; Vederas, J.C.; van Belkum, M.J. The expanding structural variety among bacteriocins from Gram-positive bacteria. FEMS Microbiol. Rev., 42, 805–828 (2018).

Sanichar, R.; Carroll, C.; Kimmis, R.; Reiz, B.; and Vederas, J.C. Dess-Martin Periodinane Oxidative Rearrangement for Preparation of α-Keto Thioesters. Org. Biomol. Chem. 16, 593-597 (2018).

Bakhtiary, A.; Cochrane, S.A.; Mercier, P.; McKay, R.T.; Miskolzie, M.; Sit, C.S.; and Vederas, J.C. Insights into the Mechanism of Action of the Two-Peptide Lantibiotic Lacticin 3147. J. Am. Chem. Soc. 139, 17803−17810 (2017).

McKinnie, S.M.K.; Wang, W.; Fischer, C.; McDonald, T.; Kalin, K.R.; Iturrioz, X.; Llorens-Cortes, C.; Oudit, G.Y.; Vederas, J.C. Synthetic modification within the ‘RPRL’ region of apelin peptides: Impact on cardiovascular activity and stability to neprilysin and plasma degradation. J. Med. Chem. 60, 6408-6427 (2017).

Sanichar, R.; Vederas, J.C. One Step Transformation of Coenzyme A Into Analogues by Transamidation. Org. Lett. 19,1950-1953 (2017).

Cochrane, S.A.;  Findlay, B.;  Bakhtiary, A.; Acedo, J.Z.; Rodriguez-Lopez, E.M.;  Mercier, P.; and Vederas, J.C. The Antimicrobial Lipopeptide Tridecaptin A Selectively Binds to Gram-Negative Lipid II. Proc. Natl. Acad. Sci. USA 2016, 113, 11561-11566.

Cochrane, R.V.K.; Sanichar, R.; Lambkin, G.R.; Reiz, B.; Xu, W.; Tang, Y.; and Vederas, J.C. Production of new cladosporin analogues by reconstitution of the polyketide synthases responsible for the biosynthesis of this antimalarial agent. Angew. Chemie Int. Ed. 2016, 55, 664-668.