The Campbell Lab at the University of Alberta
Engineering optogenetic tools for cell biology and neuroscience
Optogenetic reporters for cell biology and neuroscience
Our goal is to create new optogenetic reporters that will enable high-speed multicolour imaging of combinations of Ca2+, voltage, and countless other cellular activities in fish, rodents, and other model organisms. Most of our work in this area has focussed on expanding our multicolour series of Genetically Encoded Ca2+ indicators for Optical imaging (GECOs). However, we have recently expanded our efforts to include voltage reporters based on both fluorescent proteins and microbial opsins, and the neurotransmitters glutamate and GABA.