Question 10


How would you isolate lidocane (1), a local anaesthetic, from a reaction mixture containing lidocane (1) and 2,6-dimethyl acetanilide (2)?


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Lidocane (1) 2,6-dimethyl acetanilide (2)
  1. Extract with 1M NaCl.
  2. Wash with 1M NaHCO3.
  3. Extract with 1M NaOH.
  4. Wash with 1M HCl.
Organic Web Chem University of Alberta