Publications
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2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987
1.
Mingguo Xu
and Liang Li, 2011,
"Validation of peptide MS/MS spectra using metabolic isotope labeling for
spectral matching-based shotgun proteome analysis", J. Proteome Res. 10, 3632-3641.
2.
Leah C. Young, Kathleen M. Bone, Peng Wang,
Fang Wu, Benjamin A Adam, Pascal Gelebart, Jelena Holovati, Liang Li, Susan
E. Andrew and Raymond Lai, 2011, "Fusion tyrosine kinase NPM-ALK
deregulates MSH2 and suppresses DNA mismatch repair function – novel insights
into a potent oncoprotein", The American Journal of Pathology, 179, 411-421.
3.
Kevin Guo, Jun Peng,
Ruokun Zhou and Liang Li, 2011, "Ion-Pairing
Reversed-Phase Liquid Chromatography Fractionation in Combination with Isotope
Labeling Reversed-Phase Liquid Chromatography-Mass Spectrometry for
Comprehensive Metabolome Profiling", J. Chromatogr.
A, 1218, 3689-3694.
4.
Fang Wu, Difei Sun, Nan Wang, Yan Gong, Liang
Li, 2011, “Comparison of
surfactant-assisted shotgun methods using acid-labile surfactants and sodium dodecyl sulfate for membrane proteome analysis”, Anal. Chim.
Acta. 698,
36-43.
5.
Azeret Zuniga and Liang Li, 2011, "Comprehensive
Analysis of Urinary Acylcarnitines by Ultra-High
Performance Liquid Chromatography Tandem Mass Spectrometry", Anal. Chim.
Acta. 689,
77-84.
6.
Kevin Guo, Fiona Bamforth
and Liang Li, 2011,
"Qualitative Metabolome Analysis of Human
Cerebrospinal Fluid by 13C-/12C-Isotope
Dansylation Labeling Combined with Liquid
Chromatography Fourier Transform Ion Cyclotron Resonance Mass
Spectrometry", J. Am.
Soc. Mass Spectrom. 22, 339-347.
7.
Melisa Clements and Liang Li, 2011,
"Strategy of Using Microsome-based Metabolite
Production to Facilitate the Identification of Endogenous Human Metabolites by
Liquid Chromatography Mass Spectrometry", Anal. Chim. Acta. 685,
36-44.
8.
Peng Wang, Fang Wu, Jingdong
Zhang, Todd McMullen, Leah C. Young, Robert
J. Ingham, Liang Li, Raymond Lai, 2011, "Serine
Phosphorylation of NPM-ALK, which is Dependent on the Auto-activation of the
Kinase Activation Loop, Contributes to its Oncogenic
Potential", Carcinogenesis.
32, 146-153.
9.
Nan Wang and Liang Li, 2010, "Reproducible
Microwave-assisted Acid Hydrolysis of Proteins Using a Household Microwave Oven
and Its Combination with LC-ESI MS/MS for Mapping Protein Sequences and
Modifications", J. Am. Soc. Mass Spectrom.
21, 1573-1587.
10. Bela Reiz and Liang Li, 2010, "Microwave-assisted
Acid and Base Hydrolysis of Intact Proteins Containing Disulfide Bonds for
Protein Sequence Analysis by Mass Spectrometry", J. Am. Soc. Mass Spectrom. 21,
1596-1605.
11. Fang Wu, Peng Wang, Jingdong Zhang, Leah
C. Young, Raymond Lai and Liang Li, 2010, "Studies of Phosphoproteomic Changes Induced by NPM-ALK Highlight
Deregulation of TNF/Fas/TRAIL Signaling Pathway in
ALK-Positive Anaplastic Large Cell Lymphoma", Molecular
& Cellular Proteomics, 9,
1616-1632.
12. Nan Wang, Mingguo Xu, Peng
Wang and Liang Li, 2010, "Development of Mass Spectrometry-Based
Shotgun Method for Proteome Analysis of 500 to 5000 Cancer Cells", Anal.
Chem. 82, 2262-2271. (Highlighted in "Research Profile" written
by R. Mukhopadhyay, "An MS method for
proteomic analysis of small samples”, Anal. Chem., 2010, 82,
p 2598)
13. Zackie Aktary, Kimberly Chapman, Le Lam, Andy Lo, Chengjie Ji, Kathryn Graham,
Lillian Cook, Liang Li, John R. Mackey and Manijeh Pasdar, 2010, “Plakoglobin
interacts with and increases the protein levels of metastasis suppressor
Nm23-H2 and regulates the expression of Nm23-H1”, Oncogene,
29,
2118–2129.
14. Peng Wang, Fang Wu, Yupo Ma, Liang Li, Raymond Lai, and Leah C. Young, 2010, “Functional
characterization of the kinase activation loop in nucleophosmin
(NPM) - anaplastic lymphoma kinase (ALK) using tandem
affinity purification and liquid chromatography-mass spectrometry”, J. Bio. Chem., 285, 95-103.
15. Kevin Guo and Liang Li, 2010,
"High Performance Isotope Labeling for Profiling
Carboxylic Acid-Containing Metabolites in Biofluids
by Mass Spectrometry", Anal.
Chem. 82, 8789-8793.
16. Avalyn E. Lewis-Stanislaus and Liang Li, 2010, "A Method for Comprehensive Analysis of Urinary Acylglycines by Using Ultra-Performance Liquid Chromatography Quadrupole Linear Ion Trap Mass Spectrometry", J. Am. Soc. Mass Spectrom. 21, 2105-2116.
2009
17. Talat Yalcin and
Liang Li, 2009, “Cobalt
Coated Substrate for Matrix-free Analysis of Small Molecules by Laser
Desorption Ionization
Mass Spectrometry”, Appl.
Surf. Sci. 256, 1309-1312.
18. Liang Li,
Ed., 2009, “MALDI Mass Spectrometry for Synthetic Polymer Analysis”, Wiley:
New York, 299 pages. (also, “Overview of MS and MALDI MS for Polymer
Analysis”, pp1-8)
19. Liang Li and Randy
M. Whittal, 2009, “Time-of-flight Mass
Spectrometry for Polymer Characterization”, in MALDI Mass Spectrometry
for Synthetic Polymer Analysis. Liang Li, Ed.; Wiley: New York,
pp27-52.
20. Sambasivarao Damaraju, Nancy Zhang, Nan Li, Lidan
Tao, Vijaya L. Damaraju,
Jennifer Dufour, Cheryl Santos, Xue-Jun
Sun, John Mackey, David S. Wishart, Carol E. Cass and
Liang Li, 2009, “Evidence for Co-purification of Micronuclei in
Sucrose Density Gradient Enriched Plasma Membranes from Cell Lines”, Anal.
Biochem. 396, 69-75.
21. Andrea G. De Souza,
Tyson J. MacCormack, Nan Wang, Liang Li and
Greg G. Goss, 2009, "Large scale proteome profile of the zebrafish
(Danio rerio) gill for physiological and biomarker discovery
studies", Zebrafish, 6, 229-238.
22. Peng Wang, Andy Lo, J.
Bryce Young, Jin Song, Raymond Lai, Norman Kneteman, Chunhai Hao and Liang Li, 2009,
“Targeted Quantitative Mass Spectrometric Identification of Differentially
Expressed Proteins between Bax-Expressing and
Deficient Colorectal Carcinoma Cells”, J. Proteome Res. 8, 3403-3414.
23. Kevin Guo and Liang Li, 2009, “Differential 12C-/13C-Isotope
Dansylation Labeling and Fast Liquid
Chromatography/Mass Spectrometry for Absolute and Relative Quantification of
the Metabolome”, Anal. Chem., 81, 3919-3932.
24. David S. Wishart, Craig Knox, An Chi Guo,
Roman Eisner, Nelson Young, Bijaya Gautam, David D. Hau, Nick Psychogios, Edison Dong, Souhaila
Bouatra, Rupasri Mandal, Igor Sinelnikov, Jianguo Xia, Leslie Jia, Joseph
A. Cruz, Emilia Lim, Constance A. Sobsey, Savita Shrivastava, Paul Huang,
Philip Liu, Lydia Fang, Jun Peng, Ryan Fradette, Dean Cheng, Dan Tzur,
Melisa Clements, Avalyn Lewis, Andrea De Souza, Azaret Zuniga, Margot Dawe, Yeping Xiong, Derrick Clive, Russ
Greiner, Alsu Nazyrova, Rustem Shaykhutdinov, Liang Li,
Hans J. Vogel, and Ian Forsythe, 2009, "HMDB: a knowledge base for
the human metabolome" Nucleic Acids Res.,
37, D603 - D610.
25. Nan Wang, Chuanhui Xie, J. Bryce Young and
Liang Li, 2009, “Off-line Two-dimensional Liquid Chromatography with
Maximized Sample Loading to Reversed-Phase LC-ESI Tandem Mass Spectrometry for
Shotgun Proteome Analysis”, Anal. Chem. 81, 1049-1060.
26. Fang Wu, Peng Wang, Leah C. Young, Raymond Lai and Liang
Li, 2009, “Proteome-wide Identification of Novel Binding Partners to the
Oncogenic Fusion Gene Protein, NPM-ALK, using Tandem
Affinity Purification and MS”, The American Journal of Pathology, 174,
361-370.
2008
27. Nan Zhang, Andrew
R. E. Shaw, Nan Li, Rui Chen, Allan Mak, Nelson Young, David Wishart
and Liang Li, 2008, “Liquid Chromatography Electrospray
Ionization and Matrix-Assisted Laser Desorption Ionization Tandem Mass
Spectrometry for the Analysis of Lipid Raft Proteome of Monocytes”,
Anal. Chim. Acta.
627, 82-90.
28. David S. Wishart, Michael J. Lewis, Joshua A. Morrissey, Mitchel D. Flegel, Kevin Jeroncic, Yeping Xiong, Dean Cheng, Roman Eisner, Bijaya
Gautam, Dan Tzur, Summit Sawhney, Fiona Bamforth, Russ
Greiner, Liang Li, 2008, "The Human Cerebrospinal Fluid Metabolome", Journal of Chromatography B. (special
issue on metabolomics), 871, 164-173.
29. Yan Gong, Nan Wang,
Fang Wu, Carol E. Cass, Sambasivarao Damaraju, John R. Mackey and Liang Li, 2008,
“Proteome Profile of Human Breast Cancer Tissue Generated by LC-ESI MS/MS
Combined with Sequential Protein Precipitation and Solubilization”,
J. Proteome Res. 7, 3583-3590.
30. Nan Wang and Liang
Li, 2008, “Exploring the Precursor Ion Exclusion Feature of LC-ESI
Quadrupole Time-of-Flight MS for Improving Protein Identification in Shotgun
Proteome Analysis”, Anal. Chem. 80, 4696-4710.
31. Joel H. Weiner and
Liang Li, 2008, "Proteome of the Escherichia coli Envelope and
Technological Challenges in Membrane Proteome Analysis", Biochimica et Biophysica
Acta (BBA) – Biomembranes
1778, 1698-1713.
32. Nan Wang, J. Bryce
Young and Liang Li, 2008, “Liquid Chromatography MALDI MS/MS for
Membrane Proteome Analysis”, In Methods in Molecular Biology, vol. 528:
Methods in the Proteomics of Membrane Proteins. Robin Wait and Matthew
Peirce, Eds., Humana Press Inc., Totowa, NJ. pp295-310.
33. Kevin Guo, Chengjie Ji
and Liang Li, 2007, "Stable-Isotope Dimethylation
Labeling Combined with LC-ESI MS for Quantification of Amine-containing
Metabolites in Biological Samples", Anal. Chem. 79,
8631-8638.
34. Mahmoud M. Yassine, Nan Guo, Hongying Zhong, Liang Li and
Charles A. Lucy, 2007 , “Off-line Coupling of Preparative
Capillary Zone Electrophoresis with Microwave-assisted Acid Hydrolysis and
Matrix-assisted Laser Desorption Ionization Mass Spectrometry for Protein
Sequencing”, Anal. Chim. Acta
. 597,
41-49.
35. Mulu Gebremedhin, Hongying Zhong, Shaohua Wang, Michael Weinfeld and Liang Li, 2007 , “Benefit of
Microwave-Assisted Acid Hydrolysis of Proteins for Mass Spectrometric Profiling
of the Human Heart Tissue Proteome”, Rapid Commun.
Mass Spectrom. 21, 2779-2783.
36. J. Bryce Young and
Liang Li, 2007 , “Impulse-Driven Heated-Droplet Deposition
Interface for Capillary and Microbore LC-MALDI MS and
MS/MS”, Anal. Chem. 79, 5927-5934.
37. Mackenzie E. Malo, Liang Li and Larry Fliegel,
2007, "Mitogen-activated
protein kinase-dependent activation of the Na+/H+ exchanger is mediated through
phosphorylation of amino acids Ser770 and Ser771", J. Bio. Chem.,
282, 6292-6299.
38. Chengjie Ji, Nan Zhang, Sambasivarao Damaraju, Vijaya L. Damaraju, Pat Carpenter, Carol E. Cass and Liang Li, 2007,
"A Study of Reproducibility of Guanidination-Dimethylation
Labeling and Liquid Chromatography Matrix-Assisted Laser Desorption Ionization
Mass Spectrometry for Relative Proteome Quantification", Anal. Chim. Acta., 585,
219-226.
39. Nan Zhang, Rui Chen, Nelson Young, David Wishart,
Philip Winter, Joel H. Weiner and Liang Li, 2007,
"Comparison of SDS- and Methanol-Assisted Protein Solubilization
and Digestion Methods for Escherichia coli Membrane Proteome Analysis by
2D-LC-MS/MS", Proteomics, 7, 484-493.
40. Nan Wang, Lauren MacKenzie, Andrea G. De Souza, Hongying
Zhong, Greg Goss and Liang Li, 2007,
"Proteome Profile of Cytosolic Component of Zebrafish Liver Generated by LC-ESI MS/MS Combined with
Trypsin Digestion and Microwave-Assisted Acid Hydrolysis ", J.
Proteome Res., 6, 263-272.
41. David S. Wishart, Dan Tzur, Craig Knox,
Roman Eisner, An Chi Guo, Nelson Young, Dean Cheng,
Kevin Jewell, David Arndt, Summit Sawhney, Chris
Fung, Lisa Nikolai, Mike Lewis, Marie-Aude Coutouly, Ian Forsythe, Peter Tang, Savita
Shrivastava, Kevin Jeroncic,
Paul Stothard, Godwin Amegbey,
David Block, David. D. Hau, James Wagner, Jessica Miniaci, Melisa Clements, Mulu Gebremedhin, Natalie Guo, Ying
Zhang, Gavin E. Duggan, Glen D. MacInnis, Alim M. Weljie, Reza Dowlatabadi, Fiona Bamforth,
Derrick Clive, Russ Greiner, Liang Li, Tom Marrie,
Brian D. Sykes, Hans J. Vogel and Lori Querengesser, 2007,
"HMDB: The Human Metabolome Database", Nucleic
Acids Res., 35, D521-D526.
42. Chengjie Ji, Andy Lo, Sandra Marcus and Liang Li, 2006,
"Effect of 2MEGA Labeling for Membrane Proteome Analysis Using LC-ESI QTOF
MS", J. Proteome Res., 5, 2567-2576.
43. Liang Li, 2006,
"MALDI Mass Spectrometry for Polymer Characterization", In "A
Practical Guide to MALDI MS", F. Hillenkamp
and J. Peter-Katalinic, Eds., Wiley-VCH, Germany
2006, in press.
44. Chengjie Ji, Zhengping Wang and Liang Li, 2006
, “Protein Mass Measurement Combined with Mass Spectrometric
Sequencing of Protein Digests for Detection and Characterization of Protein
Modifications”, Canadian Journal of Chemistry , 84 ,
986-997.
45. Bernd O. Keller and
Liang Li, 2006, “Three-Layer Matrix/Sample Preparation Method
for MALDI MS Analysis of Low Nanomolar Protein
Samples”, J. Am. Soc. Mass Spectrom. 17,
780-785.
46. J. Bryce Young and
Liang Li, 2006, “Coupling of LC and MALDI-MS: techniques,
instrumentation and application”, In "Encyclopedia of Mass
Spectrometry: Hyphenated Methods", W. M. A. Niessen,
Ed., Elsevier,
47. J. Bryce Young and
Liang Li, 2006, “Impulse-Driven Liquid-Droplet Deposition Interface for
Combining LC with MALDI MS and MS/MS”, J. Am. Soc. Mass Spectrom.
17, 325-334.
48. Jacek P. Dworzanski, Samir V. Deshpande, Rui Chen, Rabih E. Jabbour, A. Peter
Snyder, and Liang Li, 2006, "Mass Spectrometry-Based
Proteomics Combined with Bioinformatic Tools for
Bacterial Classification", J. Proteome Res. 5, 76-87.
49. Chengjie Ji, Nan Guo and Liang Li, 2005,
“Differential
Dimethyl Labeling of N-termini of Peptides after Guanidination for Proteome Analysis”, J. Proteome
Res. 4, 2099-2108.
50. Nan Li, Nan Wang,
Jing Zheng, X. Michael Liu, O. William Lever, Paul M.
Erickson, and Liang Li, 2005, “Characterization of Human Tear
Proteome Using Multiple Proteomic Analysis Techniques”, J. Proteome
Res. 4, 2052-2061.
51. Sharon Barker,
Michael Weinfeld, Jing Zheng,
Liang Li, and David Murray, 2005, "The identification of
mammalian proteins crosslinked to DNA by ionizing
radiation ", J. Biol. Chem., 280, 33826-33838.
52. Jing Zheng,
53. Sharon Barker,
David Murray, Jing Zheng, Liang Li, and Michael Weinfeld, 2005, “A Method for the Isolation
of Covalent DNA-Protein Crosslinks Suitable for
Proteomics Analysis”,
Anal. Biochem., 334,
204-215.
54. Chengjie Ji, Laiji Li, Mulu
Gebre, Manijeh Pasdar and Liang Li, 2005, " Identification and
Quantification of Differentially Expressed Proteins in E-Cadherin
Deficient SCC9 Cells and SCC9 Transfectants
Expressing E-Cadherin by Dimethyl
Isotope Labeling, LC-MALDI MS and MS/MS", J. Proteome Res. 4,
1419-1426.
55. Chengjie Ji and Liang Li, 2005, "Quantitative Proteome
Analysis Using Differential Stable Isotopic Labeling and Microbore
LC-MALDI MS and MS/MS", J. Proteome Res. 4,
734-742.
56. Hongying Zhong and Liang Li, 2005, "An Algorithm for
Interpretation of Low Energy Collision-Induced Dissociation Product Ion Spectra
for de novo Sequencing of Peptides", Rapid Commun.
Mass Spectrom. 19, 1084-1096.
57. David Craft and
Liang Li, 2005, "An Integrated Sample Processing System Involving
On-Column Protein Adsorption, Sample Washing, and Enzyme Digestion for Protein
Identification by LC-ESI MS/MS", Anal. Chem. 77, 2649-2655.
58. Jacek Stupak, Huaizhi Liu, Zhengping Wang,
Brenda J. Brix, Larry Fliegel,
and Liang Li, 2005, "Nanoliter Sample
Handling Combined with Microspot MALDI-MS for
Detection of Gel-Separated Phosphoproteins", J.
Proteome Res. 4, 515-522.
59. Hongying Zhong, Sandra Marcus and Liang Li, 2005,
"Microwave-Assisted Acid Hydrolysis of Proteins Combined with LC MALDI
MS/MS for Protein Identification", J. Am. Soc. Mass Spectrom,
16, 471-481.
60. Yong Zheng, Huaizhi Liu, Jason
Coughlin, Jing Zheng, Liang Li, James C. Stone, 2005,
"Phosphorylation of RASGRP3 on Threonine 133
Provides a Mechanistic Link between PKC and RAS Signaling Systems in B
Cells", Blood, 105, 3648-3654.
61. Chang Xiao, Bao Feng Yang, Jin H. Song,
Howard Schulman, Liang Li and Chunhai Hao, 2005, "Inhibition of CaMKII-mediated
c-FLIP Expression Sensitizes Malignant Melanoma Cells to TRAIL-Induced
Apoptosis", Experimental Cell Research, 304, 244-255.
62. Chris McDonald and
Liang Li, 2005, "Limited Proteolysis Combined with Isotope Labeling
and Quantitative LC-MALDI MS for Monitoring Protein Conformational Changes: A
Study on Calcium-Binding Sites of Cardiac Troponin
C", Analytica Chimica
Acta (Special Issue on Protein Interactions), 534,
3-10.
63. Hongying Zhong, Ying Zhang, Zhihui Wen and Liang Li, 2004, "Protein Sequencing by
Mass Analysis of Polypeptide-Ladders after Controlled Protein Hydrolysis",
Nature Biotechnology, 22, 1291-1296.
64. Hongying Zhong, Sandra Marcus and Liang Li, 2004,
"Two-dimensional Mass Spectra Generated from the Analysis of 15N-Labeled
and Unlabeled Peptides for Efficient Protein Identification and de novo Peptide
Sequencing", J. Proteome Res., 3, 1155-1163.
65. Lidan Tao, Xinlei Yu, A. Peter Snyder, and Liang Li, 2004,
"Bacterial Identification by Protein Mass Mapping Combined with an
Experimentally-Derived Protein Mass Database", Anal. Chem., 76,
6609-6617.
66. Nan Li, Nan Zhang,
Allan Mak, Andrew R. E. Shaw, and Liang Li, 2004,
"Lipid Raft Proteomics: Analysis of In-Solution Digest of SDS-Solubilized
Lipid Raft Proteins by LC-MALDI Tandem Mass Spectrometry", Proteomics,
4, 3156-3266.
67. Huaizhi Liu, Jacek Stupak, Jing Zheng, Bernd
O. Keller, Brenda J. Brix, Larry Fliegel,
and Liang Li, 2004, "Open Tubular Immobilized Metal-Ion Affinity
Chromatography Combined with MALDI MS and MS/MS for Identification of Protein
Phosphorylation Sites", Anal. Chem., 76, 4223-4232.
68. Jacek P. Dworzanski, A. Peter Snyder, Rui
Chen, Haiyan Zhang, David Wishart,
Liang Li, 2004, "A Proteomic Approach for Identification of
Bacteria Using Tandem Mass Spectrometry Combined with a Translatome
Database and Statistical Scoring", Anal. Chem., 76,
2355-2366.
69. Nan Zhang and Liang
Li, 2004, "Effects of Common Surfactants on Protein Digestion and
MALDI MS Analysis of the Digested Peptides Using Two-Layer Sample
Preparation", Rapid Commun. Mass Spectrom., 18, 889-896.
70. Boyan Zhang, Chris
McDonald, and Liang Li, 2004, "Combining Liquid Chromatography with
MALDI Mass Spectrometry Using a Heated Droplet Interface", Anal. Chem.,
76, 992-1001.
71. Nan Zhang, Nan Li,
and Liang Li, 2004, "Liquid Chromatography MALDI MS/MS for
Comprehensive Membrane Proteome Analysis", J. Proteome Res., 3,
719-727.
72. A. Ghahary, F. Krimi-Busheri, Y. Marcoux, Y. Li, E.E. Tredget,
R.T. Kilani, L. Li, J. Zheng,
A. Karami, B. Keller, M. Weinfeld,
2004, "Keratinocyte Releasable Stratifin Functions as a Potent Collagenase
Stimulating Factor in Fibroblasts", J. Investigative Dermatology, 122(5),
1188-1197.
73. Andrew R. Shaw and
Liang Li, 2003, "Exploration of the Functional Proteome: Lessons
from Lipid Rafts", Current Opinion in Molecular Therapeutics, 5,
294-301.
74. G. Tarikere, W.Q. Li, S. Catalano, J. Bogenberger,
J. Zheng, B. Keller, J. Vialard,
M. Janicot, L. Li, Y. Hitoshi, D.G. Payan, D.C. Anderson, 2003, "Cellular
Interacting Proteins of Functional Screen-Derived Antiproliferative
and Cytotoxic Peptides Discovered Using Shotgun
Peptide Sequencing", Chemistry & Biology, 10, 927-937.
75. Knoblach, B.; Keller, B.O.;
Groenendyk, J.; Aldred, S.;
Zheng, J.; Lemire, B.D.;
Li, L.; Michalak, M. 2003, "ERp19 and
ERp46, new members of the thioredoxin family of
endoplasmic reticulum proteins", Molecular and Cellular Proteomics,
2, 1104-1119.
76. Thuy Tien T. Quach, Nan Li, Dawn P.
Richards, Jing Zheng, Bernd O. Keller, and Liang Li, 2003,
"Development and Applications of In-Gel CNBr/Trypsin Digestion Combined with Mass Spectrometry for the
Analysis of Membrane Proteins", J. Proteome Res., 2,
543-552.
77. Alan Doucette,
David Craft and Liang Li, 2003, "Mass Spectrometric Study of the
Effects of Hydrophobic Surface Chemistry and Morphology on the Digestion of
Surface-Bound Proteins", J. Am. Soc. Mass Spectrom.,
14(3), 203-214.
78. Nan Li, Allan Mak, Dawn P. Richards, Claudia Naber,
Bernd O. Keller, Liang Li and Andrew R. Shaw, 2003, "Monocyte Lipid Rafts Contain Proteins Implicated in
Vesicular Trafficking and Phagosome Formation", Proteomics,
3, 536-548.
79. David Craft, Alan
Doucette and Liang Li, 2002, "Microcolumn
Capture and Digestion of Proteins Combined with Mass Spectrometry for Protein
Identification", Journal of Proteome Research, 1, 537-547.
80. Wojciech Gabryelski and Liang Li, 2002, "Photo-induced
dissociation of electrospray generated ions in an ion
trap/time-of-flight mass spectrometer using a pulsed CO2 laser", Rapid Commun. Mass Spectrom., 16,
1805-1811.
81. Talat Yalcin, William E. Wallace, Charles M. Guttman,
and Liang Li, 2002, "Metal Powder Substrate-Assisted Laser
Desorption Ionization Mass Spectrometry for Polyethylene Analysis", Anal.
Chem., 74, 4750-4756.
82. Zhengping Wang, Kevin
Dunlop, S. Randolph Long, Liang Li, 2002, "Mass Spectrometric
Methods for Generation of Protein Mass Database Used for Bacterial
Identification", Anal. Chem., 74, 3174-3182.
83. Bernd O. Keller, Zhengping Wang, and Liang Li, 2002, "Low-Mass
Proteome Analysis Based on HPLC Fractionation, Nanoliter
Protein Concentration/Digestion, and Microspot MALDI
MS", Journal of Chromatography B, Special Issue on Proteomics and
Genomics, 782, 317-329.
84. F. Karimi-Busheri, Y. Marcoux, E. E.
Tredget, L. Li, J. Zheng,
M. Ghoreishi, M. Weinfeld,
and A. Ghahary, 2002, "Expression of a
Releasable Form of Annexin II by Human Keratinocytes", Journal of Cellular Biochemistry,
86, 737-747.
85. Rui Chen, Xinlei Yu, and Liang Li, 2002,
"Characterization of Poly(Ethylene Glycol) Esters Using Low Energy
Collision-Induced Dissociation in Electrospray
Ionization Mass Spectrometry", J. Am. Soc. Mass Spectrom.,
13, 888-897.
86. Nan Zhang and Liang
Li, 2002, "Ammonium Dodecyl Sulfate as an
Alternative to Sodium Dodecyl Sulfate for Protein
Sample Preparation with Improved Performance in MALDI Mass Spectrometry", Anal.
Chem., 74,1729-1736.
87. Ken K.C. Yeung, Andrea G. Kiceniuk, and
Liang Li, 2001, "Capillary Electrophoresis Using a
Surfactant-treated Capillary Coupled with Offline Matrix Assisted Laser
Desorption Mass Spectrometry for High Efficiency and Sensitivity Detection of
Proteins", J. Chromatogr. A., 931,
153-162.
88. Rui Chen, Talat Yalcin, William E. Wallace,
Charles M. Guttman, and Liang Li, 2001, "Laser
Desorption Ionization and MALDI Time-of-Flight Mass Spectrometry for Low
Molecular Mass Polyethylene Analysis", J. Am. Soc. Mass Spectrom., 12, 1186-1192.
89. Kevin Y. Dunlop and
Liang Li, 2001, "Automated mass analysis of low-molecular-mass
bacterial proteome by liquid chromatography-electrospray
ionization mass spectrometry", J. Chromatogr.
A., 925, 123-132.
90. Bernd O. Keller and
Liang Li, 2001, "Detection of 25,000 Molecules of Substance P by
MALDI-TOF Mass Spectrometry and Investigations into the Fundamental Limits of
Detection in MALDI", J. Am. Soc. Mass Spectrom.,
12, 1055-1063.
91. Bernd O. Keller and
Liang Li, 2001, "Nanoliter Solvent
Extraction Combined with Microspot MALDI TOF Mass
Spectrometry for the Analysis of Hydrophobic Biomolecules",
Anal. Chem., 73, 2929-2936.
92. Nan Zhang, Alan
Doucette and Liang Li, 2001, "Two-Layer Sample Preparation Method
for MALDI Mass Spectrometric Analysis of Protein and peptide Samples Containing
Sodium Dodecyl Sulfate", Anal. Chem., 73,
2968-2975.
93. Alan Doucette and Liang
Li, 2001, "Investigation of the Applicability of a Sequential
Digestion Protocol Using Trypsin and Leucine Aminopeptidase M for
Protein Identification by MALDI-TOF Mass Spectrometry", joint-issues of Proteomics,
1, 987-1000 and European Journal of Mass Spectrometry, 7,
157-170.
94. Tony K.-K. Mong, Aizhen Niu,
Hak-Fun Chow, Chi Wu, Liang Li, and Rui Chen, 2001 "beta-alanine-based
dendritic beta-peptides: Dendrimers
possessing unusually strong binding ability towards protic
solvents and their self-assembly into nanoscale
aggregates through hydrogen-bond interactions", Chem. Eur. J., 7,
686-699.
95. Rui Chen, Amy M.
Tseng, Mary Uhing, L. Li, 2001,
"Application of an Integrated Matrix-Assisted Laser Desorption/Ionization
Time-of-Flight, Electrospray Ionization Mass
Spectrometry and Tandem Mass Spectrometry Approach to Characterizing Complex Polyol Mixtures", J. Am. Soc. Mass Spectrom., 12, 55-60.
96. Kalal Derhami, Jing Zheng, Liang Li,
Johan F. Wolfaardt, and Paul G. Scott, 2001,
"Proteomic Analysis of Human Skin Fibroblasts Grown on Titanium: a Novel
Approach to Study Molecular Biocompatibility", Journal of Biomedical
Materials Research, 56, 234-244.
97. Rui Chen and Liang Li,
2001, "Reactions of Atomic Transition-Metal Ions with Long-Chain Alkanes", J. Am. Soc. Mass Spectrom.,
12, 367-375.
98. Rui Chen and Liang Li,
2001, "Lithium and Transition Metal Ions Enable Low Energy
Collision-Induced Dissociation of Polyglycols in Electrospray Ionization Mass Spectrometry", J. Am.
Soc. Mass Spectrom., 12, 832-839.
99. B.O. Keller, L. Li,
2000, "Discerning
100. A. Doucette, D.
Craft, L. Li, 2000, "Protein Concentration and Enzyme Digestion on Microbeads for MALDI-TOF Peptide Mass Mapping of Proteins
from Dilute Solutions", Anal. Chem., 72, 3355-3362.
101. T. Yalcin, W. Gabryelski, L. Li, 2000,
"Structural Analysis of Polymer End Groups by Electrospray
Ionization High-Energy Collision-Induced Dissociation Tandem Mass
Spectrometry", Anal. Chem., 72, 3847-3852.
102. K.G. Lichtenwalter, A. Apffel, J. Bai, J.A. Chakel, Y.Q. Dai, K.M. Hahnenberger, L. Li, W.S. Hancock, 2000,
"Approaches to Functional Genomics: Potential of MALDI-TOF Mass
Spectrometry Combined with Separation Methods for the Analysis of DNA in
Biological Samples", J. Chromatogr. B, 745,
231-241.
103. L. Li, 2000,
"Mass Spectrometry for Polymer Characterization", Polymer Prepr., 41, 627-628.
104. Rui Chen, Nan Zhang,
Amy M. Tseng, Liang Li, 2000, "Effects of MALDI Experimental
Conditions on Quantitative Composition Analysis of Ethylene Oxide/Propylene
Oxide Copolymer", Rapid Commun. Mass Spectrom., 14, 2175-2181.
105. W. Gabryelski, L. Li, 1999, "Photo-Induced
Dissociation of Electrospray Generated Ions in an Ion
Trap/Time-of-Flight Mass Spectrometer", Rev. Sci. Instrum.,
70, 4192-4199.
106. M.A. Jeannot, J. Zheng, L. Li, 1999,
"Observation of SDS-PAGE Gel-Induced Protein Modifications and Its
Implications for Accurate Molecular Weight Determination of Gel-Separated
Proteins by MALDI TOFMS", J. Am. Soc. Mass Spectrom.,
10, 512-520.
107. Y.Q. Dai, R.M. Whittal, L. Li, 1999, "Two-Layer Sample
Preparation: an Effective Method for MALDI-MS Analysis of Complex Peptide and
Protein Mixtures", Anal. Chem., 71, 1087-1091.
108. Y.Q. Dai, L. Li,
D.C. Roser, S.R. Long, 1999, "Detection
and Identification of Low-Mass Peptides and Proteins from Solvent Suspensions
of Escherichia coli by HPLC Fractionation and MALDI Mass
Spectrometry", Rapid Commun. Mass Spectrom., 13, 73-78.
109. R.M. Whittal, B.O. Keller, L. Li, 1998, "Nanoliter Chemistry Combined with Mass Spectrometry for
Peptide Mapping of Proteins from Single Mammalian Cell Lysates",
Anal. Chem., 70, 5344-5347.
110. T. Yalcin, Y.Q. Dai, L. Li, 1998, " MALDI-TOF Mass
Spectrometry for Polymer Analysis: Solvent Effect in Sample Preparation", J.
Am. Soc. Mass Spectrom., 9, 1303-1310.
111. D.C. Schriemer, D.R. Bundle, L. Li, O. Hindsgaul,
1998, "Micro-scale Frontal Affinity Chromatography with Mass Spectrometric
Detection : A New Method for the Screening of Compound Libraries", Angewandte Chemie,
Int. Ed. 37, 3383-3387.
112. T. Yalcin, W. Gabryelski, L. Li, 1998,
"Dissociation of Protonated Phenylthiohydantoin
Amino Acids and Phenylthiocarbamoyl-Dipeptides",
J. Mass Spectrom., 33, 543-553.
113. W. Gabryelski, R.W. Purves, L. Li, 1998,
"Characterization of an Electrospray Ionization
Ion Trap/Linear Time-of-Flight Mass Spectrometer for Phenylthiohydantoin
(PTH)-Amino Acid Analysis", Int. J. Mass Spectrom.
Ion Processes, 176, 213-225.
114. R.W. Purves, W. Gabryelski, L.Li, 1998, "Investigation of the Quantitative
Capabilities of an Electrospray Ionization
Ion-Trap/Linear Time-of-Flight Mass Spectrometer", Rapid Commun. Mass Spectrom., 12,
695-700.
115. Z.P. Wang, L.M. Russon, L. Li, D.C. Roser, S.R.
Long, 1998, "Investigation of Spectral Reproducibility in Direct
Analysis of Bacteria Proteins by MALDI-TOF MS", Rapid Commun. Mass Spectrom., 12,
456-464.
116. D.C. Schriemer, T. Yalcin, L. Li, 1998,
"MALDI Mass Spectrometry Combined with Avidin-Biotin
Chemistry for the Analysis of Protein Modifications", Anal. Chem., 70,1569-1575.
117. H.H. Zhu, T. Yalcin, L. Li, 1998, "Analysis of the Accuracy
of Determining Average Molecular Weights of Narrow Polydisperse
Polymers by MALDI Time-of-Flight Mass Spectrometry", J. Am. Soc. Mass Spectrom., 9, 275-281.
118. S.B. Chun, C.D.
Han, S.F. Hahn, S.Q. Harper, P.J. Savickas, D.M. Meunier, L. Li, T. Yalcin, 1998,
"Phase Behavior of Polystyrene/Polybutadiene and
Polystyrene/Hydrogenated Polybutadiene Mixtures:
Effect of the Microstructure of Polybutadiene", Macromolecules,
31, 394-402.
119. R.M. Whittal, L.M. Russon, L. Li, 1998,
"Development of LC-MS Using Continuous-Flow MALDI Time-of-Flight Mass
Spectrometry", J. Chromatogr. A., 794,
367-375.
120. D.C. Schriemer, L. Li, 1997, "Mass Discrimination in
the Analysis of Polydisperse Polymers by MALDI
Time-of-Flight Mass Spectrometry. 1. Sample Preparation and
Desorption/Ionization Issues", Anal. Chem., 69, 4169-4175.
121. D.C. Schriemer, L. Li, 1997, "Mass Discrimination in
the Analysis of Polydisperse Polymers by MALDI
Time-of-Flight Mass Spectrometry. 2. Instrumental Issues", Anal. Chem.,
69, 4176-4183.
122. T.
123. R.M. Whittal, L. Li, 1997, "Time-Lag Focusing
Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass
Spectrometry", American Laboratory, 28, 30-36.
124. Y.Q. Dai, R.M. Whittal, C.A. Bridges, Y. Isogai,
O. Hindsgaul, L. Li, 1997,
"Matrix-Assisted Laser Desorption Ionization Mass Spectrometry for the
Analysis of Monosulfated Oligosaccharides", Carbohydrate
Research, 304, 1-9.
125. R.W. Purves, L. Li, 1997, "Development and
Characterization of an Electrospray Ionization Ion
Trap/Linear Time-of-Flight Mass Spectrometer", J. Am. Soc. Mass Spectrom., 8, 1085-1093.
126. R.W. Purves, W. Gabryelski, L. Li, 1997,
"The Effect of Using Silicon Based Diffusions Pump Fluid on Spectral
Quality in an Electrospray Ionization Ion
Trap/Time-of-Flight Mass Spectrometer", Rev. Sci. Instrum.,
68, 3252-3253.
127. R.M. Whittal, D.C. Schriemer, L. Li, 1997,
"Time-Lag focusing MALDI Time-of-Flight Mass Spectrometry for Industrial
Polymer Characterization; Oligomer Resolution, Mass
Accuracy, and Average Weight Information", Anal. Chem., 69,
2734-2741.
128. R.M. Whittal, L.M. Russon, S.R.
Weinberger, L. Li, 1997, "Functional Wave Time-Lag Focusing MALDI
in a Linear Time-of-Flight Mass Spectrometer; Improved Mass Accuracy", Anal.
Chem., 69, 2147-2153.
129. D.C. Schriemer, R.M. Whittal, L. Li, 1997,
"Analysis of Structurally Complex Polymers by Time-Lag Focusing
Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass
Spectrometry", Macromolecules, 30, 1955-1963.
130. L. Li, R.E.
Golding, R.M. Whittal, 1996, "Analysis of
Single Mammalian Cell Lysates by Mass
Spectrometry", J. Am. Chem. Soc., 118, 11662-11663.
131. D.C. Schriemer, Y.Q. Dai, L. Li, 1996, "Effect of
Sample Compositions on Chemical Analysis Using Matrix-Assisted Laser Desorption
Ionization Mass Spectrometry", Proc. SPIE-Int. Soc. Opt. Eng., 2835,
95-106.
132. Y.Q. Dai, R.M. Whittal, L. Li, S.R. Weinberger, 1996,
"Accurate Mass Measurement of Oligonucleotides
using a Time-Lag Focusing MALDI Time-of-Flight Mass Spectrometer", Rapid
Commun. Mass Spectrom.,
10, 1792-1796.
133. D.C. Schriemer, L. Li, 1996, "Combining Avidin-Biotin Chemistry with Matrix-Assisted Laser
Desorption Ionization Mass Spectrometry", Anal. Chem., 68,
3382-3387.
134. Y.Q. Dai, R.M. Whittal, L. Li, 1996, "Confocal
Fluorescence Microscopic Imaging for Investigating the Analyte
Distribution in MALDI Matrices", Anal. Chem., 68, 2494-2500.
135. D.C. Schriemer, L. Li, 1996, "Detection of High
Molecular Weight Polystyrene by MALDI Mass Spectrometry", Anal. Chem.,
68, 2721-2725. (Accelerated Article)
136. S. Lee, M.A. Winnik, R.M. Whittal, L. Li, 1996,
"Synthesis of Symmetric Fluorescently Labeled Polyethylene Glycols Using Phosphoramidites of Pyrenebutanol
and Their Characterization by MALDI Mass Spectrometry", Macromolecules,
29, 3060-3072.
137. D.C. Schriemer, L. Li, 1996, "Surface Analysis of
Bulk Polymers Using Laser-Induced Photoelectron Ionization with Laser
Desorption in a Time-of-Flight Mass Spectrometer", Anal. Chem., 18,
250-256.
138. R.M. Whittal, L. Li, S. Lee, M. A. Winnik,
1996, "Characterization of Pyrene
End-Labeled Polyethylene Glycol by High Resolution MALDI Time-of-Flight Mass
Spectrometry, Macromol. Rapid Commun., 17, 59-64.
139. R.W. Purves, L. Li, 1995, "Development of an Ion
Trap/Linear Time-of-Flight Mass Spectrometer with Electrospray
Ionization for Microcolumn Liquid Chromatography
Detection", J. Microcolumn Separation,
7, 603-610.
140. R.M. Whittal, M.M. Palcic, O. Hindsgaul, L. Li, 1995, "Direct Analysis of
Enzymatic Reactions of Oligosaccharides in Human Serum Using Matrix-Assisted
Laser Desorption Ionization Mass Spectrometry", Anal. Chem., 67,
3509-3514.
141. D.S. Nagra, L. Li, 1995, "Liquid
Chromatography/Time-of-Flight Mass Spectrometry with Continuous-Flow
Matrix-Assisted Laser Desorption Ionization", J. Chromatogr.
A, 711, 235-245.
142. R.M. Whittal, L. Li, 1995, "High Resolution
Matrix-Assisted Laser Desorption Ionization in a Linear Time-of-Flight Mass
Spectrometer", Anal. Chem., 67, 1950-1954. (Accelerated
Article)
143. D.C. Schriemer, L. Li, 1995, "A Dual Ionization
Source with Laser Desorption Sample Introduction in a Time-of-Flight Mass
Spectrometer", Instrum. Science &
Technology, 23, 4-10.
144. D.C. Schriemer, L. Li, 1995, "Laser-Induced Surface
Ionization in a Time-of-Flight Mass Spectrometer", Rev. Sci.Instrum., 66, 55-62.
145. A.P.L. Wang, X.J. Guo, L. Li, 1994, "Liquid
Chromatography/Time-of-Flight Mass Spectrometry with a Pulsed Sample
Introduction Interface", Anal. Chem., 66, 3664-3675.
146. L.D. Coulson, D.S. Nagra, X.J. Guo, R.M. Whittal, L. Li, 1994,
"A Mass Spectral Recording and Storing System Based on GPIB Data Transfer
for Laser Ionization Time-of-Flight Mass Spectrometry", Appl. Spectrosc., 48, 1125-1131.
147. J.Y. Zhang, D.S. Nagra, L. Li, 1993, "Molecular Cooling and
Supersonic Jet Formation in Laser Desorption", Anal. Chem., 65,
2812-2818.
148. L. Li, A.P.L. Wang,
L.D. Coulson, 1993, "Continuous-Flow
Matrix-Assisted Laser Desorption Ionization Mass Spectrometry", Anal.
Chem., 65, 493-495.
149. D.S. Nagra, J.Y. Zhang, A.P.L. Wang, L. Li, 1992, "Multiphoton Ionization Study of Water and Ammonia
Elimination from Dipeptides with Pulsed Rapid Heating
and Laser Desorption for Sample Vaporization", Int. J. Mass Spectrom. Ion Processes, 116, 127-142.
150. A.P.L. Wang, L. Li,
1992, "Pulsed Sample Introduction Interface for Combining Flow
Injection Analysis with Multiphoton Ionization Time-of-Flight
Mass Spectrometry", Anal. Chem., 64, 769-775.
1. J.Y. Zhang, D.S. Nagra, L. Li, 1991, "Measurement of Gas-Phase
Ultraviolet-Visible Absorption Spectra of Thermally Labile Molecules with a
Pulsed Rapid Heating Technique for sample Vaporization", Anal. Chem.,
63, 2995-2999.
2. J.Y. Zhang, D.S. Nagra, A.P.L. Wang, L. Li, 1991, "On the
Capability of Multiphoton Ionization Mass
Spectrometry for Isomer Discrimination: Mass Spectra of Positional Isomers of
Aromatic Molecules", Int. J. Mass Spectrom.
Ion Processes, 110, 103-122.
3. D.S. Nagra. J.Y. Zhang, L. Li, 1991, "Pulsed Rapid
Heating Method for Volatilization of Biological Molecules in Multiphoton Ionization Mass Spectrometry", Anal.
Chem., 63, 2188-2193.
4. A.P.L. Wang, L. Li,
1991, "A Method for Background Reduction in a Supersonic Jet Multiphoton Ionization Reflectron
Time-of-Flight Mass Spectrometer", Appl. Spectrosc.,
45, 969-976.
5. L. Li, A.M. Hogg,
A.P.L. Wang, J-Y. Zhang, and D.S. Nagra, 1991,
"Pulsed Fast Atom Bombardment Sample Desorption With Multiphoton
Ionization in a Supersonic Jet/Reflectron
Time-of-Flight Mass Spectrometer", Anal. Chem., 63, 974-980.
6. A.P.L. Wang, J-Y.
Zhang, D.S. Nagra and L. Li, 1991,
"Signal Enhancement by Using a Planar Laser Beam for Multiphoton
Ionization in a Supersonic Jet/Reflectron
Time-of-Flight Mass Spectrometer", Appl. Spectrosc.,
45, 304-306.
7. D.M. Lubman, L. Li, 1990, "Resonant Two-Photon
Ionization Spectroscopy of Biological Molecules in Supersonic Jets Volatilized
by Pulsed Laser Desorption", in Lasers and Mass Spectrometry, D.M. Lubman (Ed.), Oxford University Press.
8. L. Li, D.M. Lubman, 1989, "R2PI Spectroscopic Analysis of
Thin-Layer Chromatography Using Pulsed Laser Desorption/Volatilization Into
Supersonic Jet Expansions", Anal. Chem., 61, 1911.
9. D.M. Lubman, L. Li, T.M. Dunn, 1989, "The 320 nm
Electronic Spectrum of Carbazole in a Jet by
Two-Photon Ionization", J. Phys. Chem., 93, 3444.
10. L. Li, D.M. Lubman, 1989, "Resonant Two-Photon Ionization
for Identification of Thermal Decomposition Products in the Laser Desorption of
Small Peptides", Rapid Commun. Mass Spectrom., 3, 12.
11. L. Li, D.M. Lubman, 1989, "Resonance Enhanced Multiphoton Ionization Spectroscopy and Mass Spectrometry
of Tyrosine-Containing Dipeptides Volatilized by
Pulsed Laser Desorption Into Supersonic Jets", Appl. Spectrosc., 43, 543.
12. L. Li, D.M. Lubman, 1989, "A High Temperature Pulsed
Solenoid Valve for Supersonic Jet Introduction Up to 550¡ãC", Rev. Sci.
Instrum., 60, 499.
13. L. Li, D.M. Lubman, 1989, "Resonance Enhanced Multiphoton Ionization of Nucleosides by Using Pulsed Laser
Desorption in Supersonic Beam Mass Spectrometry", Int. J. Mass Spectrom. Ion Processes, 88, 197.
14. L. Li, D.M. Lubman, 1988, "Resonant Two-Photon Ionization
Spectroscopic Analysis of Indole and Catechol Derivatives Using Pulsed Laser Desorption with
Entrainment Into Supersonic Jet Expansions", Anal. Chem., 60,
2591.
15. L. Li, D.M. Lubman, 1988, "Resonant Two-Photon Ionization
of Enkephalins and Related Peptides Using Pulsed
Laser Desorption in Supersonic Beam Mass Spectrometry", Anal. Chem.,
60, 1409.
16. L. Li, D.M. Lubman, 1988, "Analytical Jet Spectroscopy of
Tyrosine and Its Analogs Using a Pulsed Laser Desorption Volatilization
Method", Appl. Spectrosc., 42,
418.
17. L. Li, D.M. Lubman, 1988, "Pulsed Laser Desorption Method
for Volatilizing Thermally Labile Molecules for Supersonic Jet
Spectroscopy", Rev. Sci. Instrum., 59,
557.
18. L. Li, D.M. Lubman, 1988, "Resonant Two-Photon Ionization
of CBZ-Derivatized Nonaromatic
Peptides Using Pulsed Laser Desorption in Supersonic Beam Mass
Spectrometry", Appl. Spectrosc., 42,
411.
19. L. Li, D.M. Lubman, 1987, "UV-Visible Absorption Spectra of
Biological Molecules in the Gas Phase Using Pulsed Laser Desorption in a Diode
Array Spectrophotometer", Anal. Chem., 59, 2538.