Glen R. Loppnow


(403) 492-9704 (office)
(403) 492-8231 (FAX)
glen.loppnow@ualberta.ca
Born: 1960-Oconomowoc, WI USA
Marital Status: Married (Julienne), 1 child (Jonathan)

Education:

  1. B. Sc./Chemistry
    1983
    Rensselaer Polytechnic Institute, Troy, NY USA
    Research:
    1982-Synthesis of Anti-cancer Agents
    Supervisor- Dr. Kevin T. Potts
    1982-1983-Senior Thesis: Conversion of CIE Coordinates to Munsell Coordinates:
    A Comparison of Two Computer Programs
    Supervisor- Dr. Fred W. Billmeyer
    Minor: Psychology

  2. M. Sc./Analytical Chemistry
    1984
    Rensselaer Polytechnic Institute, Troy, NY USA
    M. Sc. Thesis:
    A Spectroscopic Comparison of Two Color Systems
    Supervisor- Dr. Fred W. Billmeyer

    Utilization of micro-reflectance spectroscopy and visual comparison of pigmented samples to evaluate a new standard color order system.

  3. Ph. D./Biophysical Chemistry
    1990
    University of California, Berkeley, CA USA
    Ph. D. Thesis:
    Excited-State Structure, Isomerization Dynamics, and the Mechanism of Wavelength Regulation in Visual Pigments.
    Supervisor-Dr. Richard A. Mathies

    Characterization of the excited-state structure and dynamics of the retinal chromophore in rhodopsin using resonance Raman intensities and holeburning spectroscopy. Determination of the mechanism of wavelength regulation in visual pigments by using resonance Raman spectroscopy of single photoreceptors at cryogenic temperatures. Elucidation of the ground state retinal binding pocket structure in rhodopsin and its effect on the photochemistry of the retinal chromophore using structural analogs. Development of biochemical preparations of rhodopsin. Performance of excited-state dynamics, and vibrational and electronic structure calculations.

Work Experience

  1. NIH Post-Doctoral Fellow
    1990-93
    Princeton University, Princeton, NJ USA
    Research:
    Dynamics of Electron Transfer Processes. Structure and Dynamics of Porphyrin Excited-states
    Supervisor-Dr. Thomas G. Spiro

    Probed dynamics of electron transfer in donor-appended porphyrins and metalloporphyrins using time-resolved picosecond absorption, cw fluorescence and time-resolved fluorescence spectroscopies. Determined initial excited-state distortions using UV resonance Raman intensities in a series of nitroaromatics with charge transfer states. Characterized porphyrin singlet and triplet excited-state structure using picosecond time-resolved resonance Raman spectroscopy.

  2. Assistant Professor
    1993-Current
    University of Alberta, Edmonton, AB Canada

Publications:(As of July 1, 1997)

  1. Webb, M. A., Kwong, C. M., and Loppnow, G. R. Excited-State Charge-Transfer Dynamics of Azurin, a Blue Copper Protein, from Resonance Raman Intensities. J. Phys. Chem. 101, 5062, 1997.
  2. Loppnow, G. R., and Fraga, E. Proteins as Solvents: Role of Amino Acid Composition in the Excited-State Charge Transfer Dynamics of Plastocyanins. J. Am. Chem. Soc. 119, 896, 1997.
  3. Mitambo, M., and Loppnow, G. R. Raman Spectroscopy: A Structural Probe of Solute-Solvent Interactions in Ethyl 4-(Dimethylamino)benzoate. Chem. Phys. Letters. 261, 691, 1996.
  4. Fraga, E., Webb, M.A., Loppnow, G.R. Charge-Transfer Dynamics in Plastocyanin, a Blue Copper Protein, from Resonance Raman Intensities. J. Phys. Chem. 100, 3278, 1996.
  5. Zhang, X., Loppnow, G. R., McDonald, R., and Takats, J. {HP(3,5-Me2pz)3}2Sm(h2-O2): First Example of a Lanthanide Superoxo Complex. J. Am. Chem. Soc. 117, 7828, 1995.
  6. Kumble, R., Loppnow, G. R., Hu, S., Mukherjee, A., Thompson, M. A., and Spiro, T. G. Studies of the Vibrational and Electronic Structure of the S1 Excited States of b-Substituted Porphyrins by Picosecond Time-resolved Resonance Raman Spectroscopy. J. Phys. Chem. 99, 5809, 1995.
  7. Kumble, R., Hu, S., Loppnow, G. R., Vitols, S. E., and Spiro, T. G. A Time-resolved Resonance Raman Study of the T1 Excited State of Zinc(II) Octaalkylporphyrins. J. Phys. Chem. 97, 10521, 1993.
  8. Loppnow, G. R., Melamed, D. M., Leheny, A. R., Hamilton, A. D., and Spiro, T. G. Excited-state Photophysics of Donor-appended Cobalt(II) Porphyrins from Picosecond Transient Absorption Spectroscopy. J. Phys. Chem. 97, 8969, 1993.
  9. Loppnow, G. R., Melamed, D. M., Hamilton, A. D., and Spiro, T. G. Charge Transfer in Covalently-linked Porphyrin-donor Complexes from Picosecond Transient Absorption Spectroscopy. J. Phys. Chem. 97, 8957, 1993.
  10. Loppnow, G. R. Excited-state Structure and Dynamics of the Retinal Chromophore in Rhodopsins from Resonance Raman Intensities and Holeburning Spectroscopy In Princeton Lectures in Biophysics. (W. Bialek, ed.), World Scientific, NJ, USA, pp. 27-68, 1992.
  11. Loppnow, G. R., Mathies, R. A., Gottfried, D. S., Middendorf, T. R., and Boxer, S. G. Photochemical Holeburning Spectroscopy of Bovine Rhodopsin and Bacteriorhodopsin. J. Phys. Chem. 96, 737, 1992.
  12. Loppnow, G. R., Miley, M. E., Mathies, R. A., Liu, R. S. H., Kandori, H., Shichida, Y., Fukada, Y., and Yoshizawa, T. Structure of the Retinal Chromophore in 7,9-Dicis Rhodopsin. Biochemistry 29, 8985, 1990.
  13. Loppnow, G. R., and Mathies, R. A. A 77 K Cold Stage for Raman Microprobes and Optical Microscopy. Rev. Sci. Instrum. 60, 2628, 1989.
  14. Loppnow, G. R., Barry, B. A., and Mathies, R. A. Why are Blue Visual Pigments Blue? A Resonance Raman Microprobe Study. Proc. Natl. Acad. Sci. USA 86, 1515, 1989.
  15. Loppnow, G. R., and Mathies, R. A. Excited-state Structure and Isomerization Dynamics of the Retinal Chromophore in Rhodopsin from Resonance Raman Intensities. Biophys. J. 54, 35, 1988.
  16. Billmeyer, F. W. Jr., and Loppnow, G. R. Accuracy of Munsell Notations in Two Japanese Color Order Systems. Color Res. and Appl. 13, 235, 1988.

Professional Society Memberships: